No, I have not tried it in any other configuration. Also, I have no idea how high the HDD temps get. I do know that my CPU temps are always between 29 and 35 degrees C, so the HDD temps cant be that high. Another thing I have tried to pay attention to is the temp ranges on the GPU and unless I am running a game that has a very high graphics load - Metro 2033, Battlefield and so on, the GPU fans never come on. I would like to add that I am also playing games at 3440x1440 which should push the GPU pretty hard.