Should note, did a similar recent exercise.
My GPU is a bit less of a monster. 
Should note that with this older hardware, and insane prices on newer hardware, the bang for your dollar can be a lot better. I upgraded my old HP z820 to 16-cores (dual 8x) and 256GB memory (DDR3) … AND an AMD Instinct MI25 GPU, for about $500. (This is not counting my time, which was not small.)