I’d like to correct you here, it’s “interleaving”.
According to much of buildzoids testing it seems that was kinda already the case with Zen 2, although he never tested it in games.
I’m going to link to one of the videos he made about that:
Since we haven’t seen any config benchmarks with 2x16GB DIMMs yet I would suggest either waiting a little bit or go with 4x8GB since that one was tested.