One option is Unraid, which is a NAS with docker and VM support (like TrueNAS Scale). I’ve been using it since 2019 on an old i7-3770. I “upgraded” it a year ago and added a bunch of HDD and it has been working great for my needs.
It is currently running a Windows 10 VM (4 cores & 16GB ram) and a bunch of docker containers (Tailscale, Jellyfin, Satisfactory server, 3x MakeMKV for 3 optical drives, etc).
For a pretty old system, it has worked surprisingly well with Unraid.
Wendell did a build with Gamer Nexis a few years ago and even setup ZFS as on the system (ZFS On Unraid? Let's Do It (Bonus Shadowcopy Setup Guide) [Project])