Board quality is a factor, but only compounding one. Memory controller is the primary limiter here. Things are likely to improve once next zen IMC will implement cudimm support.
Its not an advice, its real world observation of behavior and nothing has changed since 7000 series, since imc is the same. 9000 brought some agesa tweaks and more time for amd to do testing.
Unless you have miracle memory kit, golden cpu and shit gold regularly, you can forget about running 4 dimms and higher jedec speeds, much less overclocking.
Most likely outcome would be running at 3600-4800 or similar speeds, with total failure to boot just as likely scenario.
Running 4x16 is foolish endeavor when 32 GB sticks are easily available and 64GB ones are incoming (cudimm ones, but cudimm can be run at stock in bypass mode).
There is detailed thread on 4 DIMM config and related issues on this board somewhere. Update your bios, accept you are trying to run unsupported config and accept failure as likely.
EDIT: This thread for 7000 series, should be broadly applicable to 9000 series as well.