Should be fine. My Truenas Core system runs on Ivybridge and is rock solid. Fast ram less important than fast networking and better storage (SSD / fast hdd)
3TiB drives? Unless you are reusing existing drives, i’d suggest 6 or 8TiB drives as the current price / capacity sweet spot. Should let you use a lot fewer bays.
As Air mentioned, it’s very hardware backwards compatible, I had it running reliably on two DDR2 test machines for 6 months without issue. Helps greatly to use an SSD or an NVMe drive as a boot drive.
i should be more clear about it. I don’t plan on using all 36 bays from day 1. I probably get some 8-10tb drives with 1 or 2 flash drives and definitely 10gb and maybe dual 10gb. I plan on vmotion all the vm to the new drives then break the vsan and going back to hard raid from those existing drives