Unresponsive USB ports?!?!

I have just recently come across this issue upon returning from my deployment. Some of the ports in the front and back have ceased functioning altogether. Bare in mind that this rig didn't see any use for the 6 months I was gone, but since then has been completely updated.

Any ideas? any input is appreciated

Are you computer savvy? if so update your drivers. if not reply and ill show you or you can look it up