Ubuntu 22.04 on Asus WRX80E Sage not detecting USB and M.2

I am hoping to get help/guidance with issues I am having with Ubuntu on a Threadripper Pro system that does not occur on Fedora or Arch/Manjaro.

  • 1 of the 3 M.2 SSDs stops being detected.
  • 7 of 13 USB ports drop power/connectivity while loading OS (2 type-a and 1 type-c on the front panel as well as 2 type-c and 4 type-a on the rear do not work).

The system is as follows:

AMD Threadripper Pro 3975WX
Asus WRX80E Sage Wifi
32GB ECC/Registered x4
WD Black SN850 2TB x3
Nvidia RTX 3090 (EVGA FTW3 Ultra)
1000W PSU (EVGA G6)

Output of ‘lspci -k’ from liveiso

00:00.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse Root Complex
    Subsystem: ASUSTeK Computer Inc. Starship/Matisse Root Complex
00:00.2 IOMMU: Advanced Micro Devices, Inc. [AMD] Starship/Matisse IOMMU
    Subsystem: ASUSTeK Computer Inc. Starship/Matisse IOMMU
00:01.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:02.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
    DeviceName:  Onboard IGD
00:03.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:04.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:05.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:07.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:07.1 PCI bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse Internal PCIe GPP Bridge 0 to bus[E:B]
    Kernel driver in use: pcieport
00:08.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Host Bridge
00:08.1 PCI bridge: Advanced Micro Devices, Inc. [AMD] Starship/Matisse Internal PCIe GPP Bridge 0 to bus[E:B]
    Kernel driver in use: pcieport
00:14.0 SMBus: Advanced Micro Devices, Inc. [AMD] FCH SMBus Controller (rev 61)
    Subsystem: ASUSTeK Computer Inc. FCH SMBus Controller
    Kernel driver in use: piix4_smbus
    Kernel modules: i2c_piix4, sp5100_tco
00:14.3 ISA bridge: Advanced Micro Devices, Inc. [AMD] FCH LPC Bridge (rev 51)
    Subsystem: ASUSTeK Computer Inc. FCH LPC Bridge
00:18.0 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 0
00:18.1 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 1
00:18.2 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 2
00:18.3 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 3
    Kernel driver in use: k10temp
    Kernel modules: k10temp
00:18.4 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 4
00:18.5 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 5
00:18.6 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 6
00:18.7 Host bridge: Advanced Micro Devices, Inc. [AMD] Starship Device 24; Function 7
01:00.0 Non-Essential Instrumentation [1300]: Advanced Micro Devices, Inc. [AMD] Starship/Matisse PCIe Dummy Function
    Subsystem: ASUSTeK Computer Inc. Starship/Matisse PCIe Dummy Function
02:00.0 Non-Essential Instrumentation [1300]: Advanced Micro Devices, Inc. [AMD] Star