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Do you have a HTML "button" or something with the "action" = to your Python script location?
Or, are you using event driven JS to call the script when the page loads or some other event? If so are you using document.write("/path/to/script.py)?
(Sorry starting at square one here - don't be offended please)
I don't know if its the best solution but for my personal server at home I was using PHP to execute python scripts and programs that I had written in C++. Over time when I gotten more comfortable with PHP, I started converting those scripts over to PHP.