i did this type of clean up for people at a computer store where i used to work on a daily basis. I still need to every once in a while. Here is my general step-by-step. (obviously some stuff wont apply but this is for any situation)
"I think i may have ___ malware or _____ virus."
1.) First thing i do is reboot the PC into SAFE MODE or DIAGNOSTIC MODE - this will ensure the lowest number of services and processes running in the background to make things easier.
2.) I manually delete the contents of all TEMP folders, and I look in Program Files, Program Files(x86), and in C:\Users\"username"\AppData\Local and Roaming and Local Low (these are Hidden Folders so you will need to reveal hidden folders in the folder options. If you do not know how to do this. stop here and take your PC to someone to have this done.) In each location I look for any folders or files with names I do not recognize - use a Google search to verify anything you are unsure about. Conduit likes to hang out here and is a know Malware and browser hijacker.
3.) Use a uninstaller like Wise Uninstaller or IOBit Uninstaller to remove anything that you do not recognize or do not want that is installed on your PC. Once Complete let the program do it's "DEEP SCAN" or whatever the program calls the equivalent action.
3.a) Use HiJack This the look for BHO's and anything labeled with (missing file.) Pay close attention to the items in this list, it is very easy to delete the wrong thing.
Restart the PC. Remain in SAFE MODE
4. Still in SAFE MODE now run MalwareBytes and eliminate anything it finds. Also run the virus scan of your choice. Microsoft Security Essentials is fine, so is just about any other under the sun.
5. Check all the shortcuts to your browsers(IE, CHROME, FireFox) on your desktop and in the launch tray. Look at Properties and the TARGET field. Ensure that no web addresses have been added to the end of the target path.
6. Remove any Addons, plugins, extensions, etc that may be causing issues, or that are unfamiliar.
7. Once this entire process is complete you can re-do all steps once more to ensure nothing made it through. Or move along.
After the fact all you need is to use malwarebytes, a basic virus software (like MSE - really you do not need more) and AdBlock or PopUpBlocker. Then just dont download or click on stupid stuff you don't need.