Can the MSI Z77A-GD65 fit 680 Direct CUII SLI
That's most definitely a chassis question. As long as the motherboard has a PCI-e x16 slot, the card will fit the motherboard, and the G65 has a few of those.
so it cant fit those cards in SLI?
Yes, the motherboard can run those two cards in SLI. You also need a proper case and PSU.