[This issue was fixed by me (see reply), but I will leave the post up]
Hi there! 
Apologies for starting my forum account with a tech support post, but I ran out of things to try myself and figured if anywhere I could most likely find help here.
I like to use Lutris and proton-GE to run Windows games under Debian systems. More specifically, I like MX Linux, because to me its Debian with a little bit of extra functionality that increases my quality of life. When I was on previous MX 21, I had no issues running games but I think something changed with MX 23, which I am running now, which is giving me a new type of issue.
The games itself all work under native Windows, and have previously worked under other versions of linux like MX 21, so its not the games themselves.
My system is:
3900X
6750XT
64GB ram (memtested)
My OS is: MX Linux 23, KDE (AHS), X server
kernel 6.1.0-10-amd64
Lutris from repo, 0.5.12
Runner: lutris-GE-Proton8-13, also tried lutris-7.2-2
My lutris install operation looks like this (some stuff is redundant I know):
$sudo apt-get install python3-launchpadlib
$sudo apt-get install software-properties-common
$sudo dpkg --add-architecture i386 && sudo apt update && sudo apt upgrade && sudo apt install libgl1-mesa-dri:i386 mesa-vulkan-drivers mesa-vulkan-drivers:i386 libgl1-mesa-dri:i386
$sudo dpkg --add-architecture i386 && sudo apt update && sudo apt install -y libasound2-plugins:i386 libsdl2-2.0-0:i386 libdbus-1-3:i386 libsqlite3-0:i386 winehq-staging vulkan-tools
I am having an issue now launching more recent games (that I am guessing are DX12 only):
This is my error log for those titles:
345583.569:00c8:00cc:err:vkd3d-proton:load_d3d12core_once: Failed to find vkd3d-proton d3d12core interfaces. Make sure d3d12core.dll is installed as well.
Monitored process exited.
Initial process has exited (return code: 1280)
Exit with return code 1280
So obviously something wrong with how it deals with DX12 but because I never had to do deal with this error before on the same machine I am unsure where to start fixing it, or what prereqs I may be missing. I understand Linux is a bit of a personal journey, as I am having to constantly save paragraphs of important text for later reference to get the most out of it. I can’t be the only one who daily drives MX 23 and also likes to play games so I’m hoping for someone to drive by and leave a hint as to whats going on. Thank you!