Involuntary window switching

I have having a issue with Windows 7 constantly keeps switching to desktop every few minutes or more frequant. I am starting to disable a lot of auto updaters and stuff. I tried disabling some of the background programs with System Mechanic, but it still happens. Also the My Computer folder opens at start up. What are the issues and how do I sovle it?

Also it does not close the window, if I am not in a full screen game, it just clicks out of the window I am in. When that happens, the little loading(or working) icon appears next to my cursor.

Sounds like you have a virus or two ... or five. Download, install, update and full scan your system with thisĀ