Help with flickering

Ok guys, I csnt find a solution. Out of nowhere wheb I use fullscreen my monitors flicker then game freezes to the point I have to crt alt delete and end task or reset the drivers for video..ive tried changing mpo and time out settings I cna only get it to work properly in windowd mode…it never did this before I have 4 mo tirls hooks up but use 2 at a time one is 138hz 4k 45 in and another is 500hz 1440p 27in monitor..also I alwysd have a usb 4 xeneon edge by corsiar for mo storing stuff…I’ve used ddu and went all the way bskc to 25v drivers for amd ps I have a new 9070xt by gigabye..it isnt a hardwsre issue like the graphics card cuz in eid was its perfdct..I don’t wa ma match the hrz then whats the point od having g a 500hz montior…I just need a solution. Plz…ive done eveyjting but reinstall windows I need new ideas…ps im changing cbales now ill update if that works