I'm currently in the process of building myself a computer (my first build ever), though I've been having a bit of trouble installing my GPU (one of these). It fits into the PCI-E slot on the motherboard just fine, though it doesn't quite line up with the expansion slots on the back of the case. All the display connections (HDMI, etc) line up with the expansion slot holes just fine, but the end of the bracket that the screws go into is about 4 or 5 mm away from the screw holes in the case. (I don't have any pictures currently sorry. If they would help to illustrate what I mean, please let me know). Is this anything to worry about, or would it be fine to screw it in anyway (without applying too much pressure) and see if it works?
Hopefully that all makes sense. If you have any questions, please let me know.