+1 to the power supply. You really REALLY won't need that much. You can even get by with a 650w. Find out for yourself http://www.extreme.outervision.com/PSUEngine
850w if you want to have some breathing room for, say, another 780.
As far as the audio, all you do is set your default audio input/output in windows, you can use any one of the included audio jacks, but I would recommend just keeping it simple and using the on-board audio header routed to the front panel of the case.
Also, I don't know what you plan on using the 4xaf120 fans for, but those fans are meant for airflow, not static pressure. If you planned on using them for the h100, they will not work very well. For that, you should go with the sp120's. Just two will be fine for the h100, because there is not much performance improvement with push-pull on that thin radiator.
For fan orientation, this is what I would do: 2 in the front as intake, 1 on the side as exhaust next to the 780, and the 2 on the h100 as exhaust, none on the back. The exhaust on the side panel would get the hot air of the 780 out of your case asap, which is what you want with that style gpu cooler. The included fractal fans are decent and very quiet, I'd say not much reason to upgrade them unless you really like the look of the corsair fans. No real reason to have an exhaust at the back, that along with the h100 and side panel fan would create a lot of negative pressure, which is bad for dust.
If you're going with the windowed side panel, where you cannot have a fan next to the 780, then 2 fans in the front as intake, one at the back as exhaust, and the h100 as exhaust.
The rest of your parts I say thumbs up to.