Is dual channel RAM preferable to single channel?
For instance;
G.SKILL Ripjaws Series 8GB (2 x 4GB) 240-Pin DDR3 SDRAM DDR3 1600 (PC3 12800) Desktop Memory Model F3-12800CL9D-8GBRL
vs
CORSAIR Vengeance LP 8GB 240-Pin DDR3 SDRAM DDR3 1600 Desktop Memory Model CML8GX3M1A1600C10
If you can have dual channel memory go for it. The performance increase isn't massive but it is there. Paired RAM is also preferable.
It depends what you want to do with it. Generally the only use for 1 stick of ram is so you can buy a second later on. If you're gaming 8gb will be fine and the 2x4 will be faster but if you are editing and on a budget buying 1x8 will be a better choice since later on you can grab a second 1x8 and throw it into the next channel. The same difference applies between 4x4 and 2x8 and so on.