Does 2 or 3 monitors effect my frame rate?

If I'm playing a full screen game on 1 monitor and have a second/third monitor plugged in not doing anything (or maybe with a webpage open) does that effect my game FPS?

 

Edit: moved to GPU section (my bad)

move me to gpu section/

I have a similar setup with 2 monitors using a 560ti and I haven't noticed any drops. They may be slight, but it's nothing big. I usually have a VM on the second screen.