Can run two different video cards (GPUS)

Here my computer plans for light to heavy edit/creative task and Gaming as while keeping two video card under $1,000 each. First is (: PNY GeForce GTX 980 4GB Video Card) for gaming and seconded is( PNY Quadro K4200 VCQK4200-PB 4GB 256-bit GDDR5 PCI Express 2.0 x16 Workstation Video Card ) for edit/creative duty's task as well.

I think it can be done but I don't know how many people do it.

As long as you can tell whatever software you're using to use a specific card for rendering you should be good.

Thank you very much your feed back!

So , I Should find group of people who do. Then ask for there extra help, if can be done by the way?