Been trying to get this happening on my dual 980TI rig,
I have a Wasabi Mango 49" 4k screen and a portrait 900p screen to the right side.
I'm using OpenBox on Ubuntu 16.10 with latest drivers (kernel4.8)
Issues I have encountered so far:
-Enabling SLI/MultiGPU in xorg.conf causes second screen to be disabled and the 4k screen to be stuck at 30hz. SLI shows as active in the nvidia-settings control panel.
-Nvidia talks about this MOSAIC SLI option but for me it only has the basic version which is for single card setup, no option shows up for SLI for this mode (as mentioned in their notes, this a premium feature?)
-Sometimes when attempting to enable the second screen I will instead get a extended PAN view on the 30hz 4k screen (because I can't select 60hz as it doesn't exist).
-I have attempted to connect the 2nd monitor to the second GPU but that didn't seem to change anything. The 2nd monitor does show up in non-SLI mode for use just fine.
-I have had some partial success with "Xinerama" but here's the catch, RandR fails and doesn't work, no solution found and its a critical component for allot of apps ;-(
PS. I'm not using TwinView option as I only want my 49" to be used for gaming.