After starting a game... Weird issue appeared

So I started Tom Clancy's The Division Beta and I have set the settings to Ultra. I have to restart the game for it to set it for real. So I suppose it's not the issue. My game crashed black screen like it was sending no more information to TV (please verify that you have plugged something to it message).

I restarted the game now with the settings at Ultra and I noticed I had no more sounds on my headphone but on my second TV that is plugged to my Motherboard's usb port. I had to unplug and plug again for it to recognize my Headphones again. Weird huh? What does it mean? Can you blow up a graphic card just by asking too much like ultra settings? What I think is wrong is that my headphones are plugged via USB.. not on my GPU...

Sorry if it's not clear, english isn't my native language.
Thanks !

Try to check the game files first.... it is possible if your game crashes that the game files are messed up in the process (if it is trying to write to a config file or something). Certainly a weird issue.