Have the side fans pull cool air in, your exhaust fan(s) - Power Supply - videocard will blow hot air out of the case.Â
Is there even a fan, or more then 1 fan in-taking cool air?
It doesn't make sense to me to have those 2 fans on the side pulling air out, it will create more dust build-up having the fans blowing inward but that's why they made dust-filters-
why not just test it to see which gives better temperatures, and if its a measley difference have them blowing out - saves on dust ^^. now to answer your real question, i would if i felt it was running too hot, or holding back overclocks and if it could be done without looking cheap/naff.
i was going for intakes because i thought there was probably a reason why most of the cases i've seen with side fans were used as intakes. (antec 300, antec 902, cm 690, etc.)
I guess i'll maybe try to mount em with some zip ties first to see the effectiveness before drilling into the side door.